Management of antiretroviral therapy failure in resource limited settings
نویسندگان
چکیده
منابع مشابه
Improving first-line antiretroviral therapy in resource-limited settings.
PURPOSE OF REVIEW Access to first-line antiretroviral therapy in resource-limited settings has increased rapidly in the last 5 years. Newer medicines with greater potency and better safety profiles open the possibility for improving first-line antiretroviral therapy for developing countries. RECENT FINDINGS Several medicines offer the potential to improve the simplicity, safety and efficacy o...
متن کاملAntiretroviral Treatment in Resource-Limited Settings 2012
1HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 2Vaccine and Infectious Disease & Public Health Science Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA 3Departments of Global Health and Epidemiology, University of Washington, Seattle, WA 98109, USA 4 Infectious Diseases Section, AIDS Program, Yale University School of Medicin...
متن کاملDiagnosis and management of antiretroviral-therapy failure in resource-limited settings in sub-Saharan Africa: challenges and perspectives.
Despite the enormous progress made in scaling up antiretroviral therapy (ART) in sub-Saharan Africa, many challenges remain, not least of which are the identification and management of patients who have failed first-line therapy. Less than 3% of patients are receiving second-line treatment at present, whereas 15-25% of patients have detectable viral loads 12 months or more into treatment, of wh...
متن کاملEvaluation of WHO Criteria for Viral Failure in Patients on Antiretroviral Treatment in Resource-Limited Settings
Our objective was to evaluate outcomes in patients with sustained viral suppression compared to those with episodes of viremia. Methods. In a prospective cohort of patients started on ART in Uganda and followed for 48 months, patients were categorized according to viral load (VL): (1) sustained-suppression: (VL ≤1,000 copies/mL) (2) VL 1,001-10,000, or (3) VL >10,000. Results. Fifty-Three (11.2...
متن کاملInfant outcomes after maternal antiretroviral exposure in resource-limited settings.
BACKGROUND AND OBJECTIVE The impact of maternal antiretrovirals (ARVs) during pregnancy, labor, and postpartum on infant outcomes is unclear. METHODS Infants born to HIV-infected mothers in ARV studies were followed for 18 months. RESULTS Between June 2006 and December 2008, 236 infants enrolled from Africa (n = 36), India (n = 47), Thailand (n = 152), and Brazil (n = 1). Exposure to ARVs i...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2012
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2012.05.116